Melatonin has the ability to reduce sleep onset time and increase sleep duration. Melatonin is a naturally occurring hormone that plays of a role in initiating and maintaining sleep and control of our 24-hour rhythms.
Melatonin is naturally occurring, produced and secreted by the pineal gland and acts on
receptors in the hypothalamus. The pineal gland is stimulated to release melatonin by the evening hours and a dark environment.
There is a melatonin secretion surge in the evening thought to be associated with the
beginning of sleep propensity. The primary physiological function is to convey information concerning the daily cycle of light and darkness to body structures. This helps us respond to changes in the light period and organizes seasonal and circadian rhythms. 3
Dosing and Administration
Physiologic doses range from 0.1 to 0.3 mg for sleep and 0.3 to 0.5 mg for phase
People who are pregnant, breastfeeding or have a history of hypertension, diabetes,
depression, autoimmune disease, and/or seizure disorders should consult with a
physician prior to the use of melatonin. Prolonged use of high doses may desensitize the melatonin receptors in the brain.